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ABSTRACT: Background
Pulmonary hypertension (PH) is characterized by elevated pulmonary pressures and right ventricular strain. Pulmonary arterial hypertension (PAH), a subtype, has a poor prognosis, especially when diagnosis is delayed. Artificial intelligence (AI) methods, including machine learning (ML) and deep learning (DL), offer potential for non-invasive prediction and risk stratification.Objective
This systematic review assesses ML and DL applications for non-invasive diagnosis, classification, and prognostication in PH and PAH, with emphasis on methodological quality and clinical applicability.Methods
A PRISMA-guided search identified studies using ML or DL on non-invasive clinical, imaging, or biomarker data, including omics and laboratory parameters. Study charact
SUBMITTER: Kramer T
PROVIDER: S-EPMC12690818 | biostudies-literature | 2025 Dec
REPOSITORIES: biostudies-literature