Relationship of admission uric acid to high density lipoprotein cholesterol ratio with unfavorable prognosis among acute ischemic stroke patients.

ABSTRACT:

Background

Acute ischemic stroke (AIS) remains a major determinant for both mortality and enduring functional impairment. High density lipoprotein cholesterol (HDL) and Uric acid (UA) have opposing effects on oxidative stress and vascular protection. The UA/HDL ratio (UHR) may reflect systemic oxidative-lipid imbalance. This study examined whether admission UHR is linked to unfavorable prognosis among individuals with AIS.

Methods

Between October 2022 and September 2024, 822 consecutive AIS patients admitted to Bethune Hospital of Shanxi were retrospectively analyzed. Inclusion required first-ever AIS confirmed by imaging findings within 72 h. The principal endpoint was the functional status assessed at 90 days. Baseline demographics, clinical features, and laboratory values

SUBMITTER: Kong X 

PROVIDER: S-EPMC12690874 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature