Integrated multi-omics reveals terpenoid-driven metabolic and transcriptional regulation underlying sweetpotato resistance to black rot disease.

ABSTRACT: Sweetpotato black rot, caused by the fungus Ceratocystis fimbriata, adversely affects yield and postharvest quality. We applied integrated transcriptomic and metabolomic profiling to elucidate resistance mechanisms in the black rot-resistant cultivar SS23 versus the susceptible cultivar GS08. Phenotypically, SS23 developed substantially milder symptoms and smaller lesions, whereas GS08 suffered extensive root damage. Multi-omics integration revealed that SS23 mounted a rapid defense response characterized by the upregulation of defense-related genes (e.g., peroxidase, chitinase) and a coordinated metabolic reprogramming that increased levels of resistance-associated compounds, including the amino acids leucine and proline and sesquiterpenoids such as plumericin. By contrast, GS08 exhibited

SUBMITTER: Zhang F 

PROVIDER: S-EPMC12690883 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature