Carbapenems versus non-carbapenems as definitive treatment for hypervirulent <i>Klebsiella pneumoniae</i> bacteremia in Taiwan.

ABSTRACT: Hypervirulent Klebsiella pneumoniae (hvKp) can cause serious community-acquired pyogenic infections and is prevalent in Asian countries. Unlike classical K. pneumoniae, which is usually multidrug resistant, hvKp is usually antimicrobial-sensitive. However, the optimal definitive treatment for hvKp bacteremia remains unclear, with carbapenems often used due to severe conditions. We aimed to compare clinical outcomes of patients with hvKp bacteremia treated with carbapenems and non-carbapenems in Taiwan. This retrospective study included patients with monomicrobial hvKp bacteremia treated with appropriate definitive therapy at Taipei Veterans General Hospital from January 2015 to December 2017. K. pneumoniae isolates carrying rmpA/rmpA2 genes were defined a

SUBMITTER: Juan C-H 

PROVIDER: S-EPMC12691612 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature