Isolation and Characterization of Extracellular Vesicles Derived from Mango Fruits.

ABSTRACT: The mango (Mangifera indica L.) is a commonly cultivated tropical fruit across the globe. It is known to be rich in carotenoids, polyphenols, and vitamins, compounds that largely account for its nutritional and medicinal properties. Although the beneficial effects of mango phytochemicals have been widely documented, virtually no studies have investigated extracellular vesicles (EVs) originating from mango fruit. In the presented work, we developed a workflow combining differential centrifugation, filtration, and size-exclusion chromatography for the isolation of EVs from mango pulp. The isolates were characterized in accordance with the guidelines of the International Society of Extracellular Vesicles recommendations. The optimized size-exclusion chromatography column, packed with S

SUBMITTER: Stec A 

PROVIDER: S-EPMC12691788 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature