Functional Genetic Frontiers in Plant ABC Transporters: Avenues Toward Cadmium Management.

ABSTRACT: Cadmium (Cd) is a pervasive and highly toxic heavy metal that severely threatens environmental integrity, agricultural systems, plant metabolism, ecosystem health, and human food safety. Plants have evolved intricate detoxification mechanisms aimed at mitigating heavy metal toxicity, in which ATP-binding cassette (ABC) transporters play pivotal roles. This article contextualizes findings on the functional genetic manipulation of plant ABC transporters in Cd-exposed species, integrating evidence from model plants, crops, and transgenic systems. Key insights reveal how these transporters contribute to Cd distribution through multiple cellular and physiological pathways. We highlight the contribution of ABC transporters both in modulating Cd accumulation in plant tissues for food safety consi

SUBMITTER: Novaes Marques D 

PROVIDER: S-EPMC12691841 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature