Preparation and Application of Magnetic Microporous Organic Networks for Rapid Adsorption Enrichment of Multiple Mycotoxins in Complex Food Matrices.

ABSTRACT: Mycotoxins commonly contaminate grains and traditional Chinese medicinal materials, posing serious health risks to humans and animals. To address this issue, a magnetic microporous organic network (MMON) was synthesized via an in situ growth method and Sonogashira-Hagihara coupling for the simultaneous adsorption of seven mycotoxins, followed by UPLC-MS/MS detection. The optimized MMON featured a high surface area, uniform micropores, and rapid magnetic separation within 5 s. Structural and compositional analyses confirmed its tailored architecture, while DFT calculations revealed a pore confinement effect, π-π stacking, and hydrophobic interactions as the primary adsorption mechanisms. A magnetic solid-phase extraction (MSPE) method using 8 mg of MMON achieved adsorption equilibrium withi

SUBMITTER: Wang C 

PROVIDER: S-EPMC12692691 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature