Dual Synthetic Pathways for Organotin-Functionalized Mesoporous Silica Nanoparticles: Targeted Therapeutic Platforms with Folic Acid and PEI Formulation.

ABSTRACT: Breast cancer is the most common cancer in women worldwide, with a high mortality rate. Moreover, the treatments currently used to address this disease are sometimes ineffective and cause numerous side effects. For this reason, the search for new treatments that can overcome these challenges is a growing field of research. One potential solution under investigation is the use of mesoporous silica nanoparticles (MSNs). These materials possess excellent properties, making them attractive as starting platforms for various compounds. In this study, different compounds with distinct properties were anchored onto these nanoplatforms. The first is polyethyleneimine (PEI), which, when formulated within the nanoparticle, increases its bioavailability. The second is folic acid (FA), a molecule that

SUBMITTER: Garcia-Almodovar V 

PROVIDER: S-EPMC12692869 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature