Procedural Challenges in Soil Sample Preparation for Pharmaceuticals Analysis.

ABSTRACT: The determination of trace levels of pharmaceuticals in complex environmental samples requires an appropriate sample preparation stage prior to final determination. Currently, special attention should be paid to pharmaceuticals extensively used on industrial farms due to their possible emission into the soil environment, which has become a public health concern. The greatest challenge in such sample analyses lies in selecting the appropriate analyte extraction procedure. To address these challenges, five sample preparation procedures were evaluated for the determination of 24 pharmaceuticals, aiming to compare analyte recovery. We focused on commonly used stages of the procedure, such as ultrasonication and filtration, to minimize potential analyte loss. Our results indicate that some comp

SUBMITTER: Fiszka Borzyszkowska A 

PROVIDER: S-EPMC12693053 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature