Block Copolymer-Sodium Oleate Complexes Through Electrostatic Interactions for Curcumin Encapsulation.

ABSTRACT: Polyelectrolyte-based complexes have attracted attention, as the interaction of the oppositely charged components results in nanoparticle formation through an easy but highly efficient method, avoiding the use of strong solvents, extreme temperatures, and toxic chemicals. Sodium oleate (NaOL) is a widely used surfactant in the pharmaceutical industry due to its availability, eco-friendliness, and low cost. In the present study, the neutral-cationic block copolymer poly(oligo(ethylene glycol) methyl ether methacrylate)-b-quaternized poly(2-(dimethylamino) ethyl methacrylate) (POEGMA-b-Q(PDMAEMA)) is mixed with the anionic surfactant sodium oleate for the formation of nanoscale polyelectrolyte complexes through electrostatic interactions. Different weight ratios of copolymer to surfactant ar

SUBMITTER: Ganou E 

PROVIDER: S-EPMC12693471 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature