Clinical Outcomes Associated with Statin Use in Pulmonary Embolism: A Systematic Review of Observational Studies.

ABSTRACT: Background: Pulmonary embolism (PE) represents one of the most serious complications of venous thromboembolism (VTE). Conflicting studies indicate that statins could play a role in preventing recurrent VTE or improving survival in patients with PE. This review aims to assess the impact of statin use on clinical outcomes in patients with PE. Methods: A systematic search was conducted in PubMed and the Cochrane Library to identify studies evaluating the impact of statin therapy in patients with PE. The search covered all records from inception to 21 September 2025. Studies were deemed eligible if they included adult patients with PE, investigated statin and reported clinical outcomes such as mortality, recurrent PE, recurrent VTE, or deep vein thrombosis (DVT). The methodologic

SUBMITTER: Alshahrani WA 

PROVIDER: S-EPMC12693536 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature