The phenotypic variation of widefins medaka is due to the insertion of a giant transposon containing a viral genome within the hoxca cluster.

ABSTRACT: Phenotypic variation in species arises from genetic differences and environmental influences on gene expression. Differences in epigenetic modifications, such as histone modifications and DNA methylation, can also contribute to phenotypic variations, even among individuals with identical genetic information. However, the underlying molecular mechanisms are not yet fully understood, particularly in vertebrates. The number of fin rays in teleosts, such as medaka, serves as a useful model for studying this variation. In a previous study, we demonstrated that the teleost Hox code plays a crucial role in determining the anterior-posterior identity necessary for the formation of dorsal and anal fins. In this study, we investigated widefins medaka, a spontaneous mutant displaying phenotypic varia

SUBMITTER: Koita R 

PROVIDER: S-EPMC12693550 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature