Extraction and Identification of Active Components from <i>Lilium lancifolium</i> Based on NADES-UHPLC-MS/MS Technology.

ABSTRACT: The bulb of Lilium lancifolium, a traditional Chinese medicine and food-homologous material, is rich in various saponins with notable pharmacological activities. However, traditional extraction methods using single solvents suffer from low efficiency, high cost, and flammability. To address these limitations, this study developed a green and efficient extraction method using natural deep eutectic solvents (NADES). Twenty-four NADES were synthesized and screened for stability, leading to the selection of fourteen for subsequent extraction of saponins from L. lancifolium, with ethanol extraction as a control. Through optimization, NADES-15, composed of choline chloride and anhydrous citric acid (2:1), was identified as the most effective solvent. Quantitative analysis revealed

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12693660 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature