Accelerometer-Based Gait Analysis as a Predictive Tool for Mild Cognitive Impairment in Older Adults.

ABSTRACT: This study explores the potential of accelerometer-based gait analysis as a non-invasive approach for predicting cognitive impairment in older adults. A total of 75 participants (61.3% female; mean age: 78.9 years), including cognitively normal individuals and patients with dementia, were enrolled. Walking data were collected using a six-axis waist-worn accelerometer during self-paced locomotion. Allan variance (AVAR), a robust statistical measure of frequency stability, was applied to characterize gait dynamics. AVAR-derived features, combined with participant age, were used as inputs to machine learning models, logistic regression and Light Gradient Boosting Machine (LightGBM) for classifying cognitive status based on Mini-Mental State Examination (MMSE) scores. LightGBM achieved superio

SUBMITTER: Shen J 

PROVIDER: S-EPMC12694434 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature