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Association between Modic changes and recurrence of lumbar disc herniation after percutaneous endoscopic lumbar discectomy: a meta-analysis.


ABSTRACT:

Purpose

This study aims to identify the association between preoperative Modic changes and the recurrence of lumbar disc herniation (LDH) in patients who have undergone percutaneous endoscopic lumbar discectomy (PELD).

Methods

The PubMed, Web of Science, EMBASE, and CNKI databases were searched from their inception until 19 March 2025. Early recurrence was defined as herniation occurring within 6 months postoperatively, whereas late recurrence referred to herniation occurring after 12 months. Odds ratios (ORs) with 95% confidence intervals (CIs) were combined, and subgroup analyses were conducted according to the recurrence type.

Results

Twenty-seven studies involving 10,116 patients were included, with the majority of studies originating from China (25/27). The recur

SUBMITTER: Li X 

PROVIDER: S-EPMC12695757 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature