Disproportionality analysis of taste disorders using the FDA adverse event reporting system and Japanese adverse drug event report databases.

ABSTRACT:

Introduction

Taste disorders, which can diminish the quality of life and potentially affect drug treatment efficacy, are adverse events that may occur with the use of various medications; however, only a few studies have comprehensively examined this relationship. Spontaneous reporting system-based databases, such as the FDA Adverse Event Reporting System (FAERS) and Japanese Adverse Drug Event Report (JADER), are efficient sources of information for patients treated with drugs; however, analyses using this type of database have some limitations. To address these gaps in knowledge, we comprehensively analyzed the association between drugs and taste disorders using the FAERS and JADER databases.

Methods

The reporting odds ratio (ROR) and Bayesian statistics (Bayesian Confiden

SUBMITTER: Kyotani Y 

PROVIDER: S-EPMC12695858 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature