Neutrophil-to-Lymphocyte Ratio as an Independent Predictor of Adverse Short-Term Functional Outcomes After Reperfusion Therapy in Acute Ischemic Stroke.

ABSTRACT:

Background and purpose

Intravenous thrombolysis (IVT) and endovascular thrombectomy (EVT) are primary treatments for acute ischemic stroke (AIS), but their efficacy is limited. This study aims to evaluate the short-term predictive value of the neutrophil-to-lymphocyte ratio (NLR) in AIS patients undergoing reperfusion therapies.

Method

AIS patients who underwent IVT and/or EVT at Chengdu Second People's Hospital were continuously enrolled from January 2020 to September 2024. NLR was calculated from blood samples taken before treatment. Primary outcomes were functional status at discharge (assessed using the modified Rankin Scale [mRS]), while secondary outcomes included in-hospital mortality and any intracranial hemorrhage (ICH). Statistical analyses included logistic regres

SUBMITTER: Li JY 

PROVIDER: S-EPMC12696041 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature