Impact of collateral flow on recanalization in different thrombectomy techniques.

ABSTRACT: Cerebral collateral status is considered an independent prognostic factor in stroke patients. We aimed to assess whether collateral extent also modifies first-pass recanalization (FPR) and distal emboli generation across different mechanical thrombectomy (MT) strategies. Two in-vitro neurovascular models were created: good (GCM) and poor collaterals model (PCM). Both were identical up to the M2 segment of the middle cerebral artery (MCA), but only the GCM included primary and secondary anastomoses. Soft (stiffness = 53.72 ± 5.32 kPa) and stiff (stiffness = 110.02 ± 10.59 kPa) clot analogs embolized the M1-MCA. The study was randomized for thrombectomy technique: direct aspiration thrombectomy, partial stent retriever retraction and complete stent retriever retraction. Outcome measures were

SUBMITTER: Jablonska M 

PROVIDER: S-EPMC12696111 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature