A three-stage sequential surgical approach to a more efficient management of clinical stage 4 diabetic foot ulcers.

ABSTRACT:

Background

It has been a great challenge to treat clinical stage 4 Diabetic foot ulcers (DFUs) due to high rates of major amputations and prolonged healing time. This study aimed to assess the effectiveness of a three-stage sequential surgical approach, which based on the Integrated Surgery Wound Treatment (ISWT) mode, to manage clinical stage 4 DFUs and compare the benefit of incorporating tibial cortex transverse transport (TTT) surgery at stage 3 treatment.

Methods

Twenty-three patients with clinical stage 4 DFUs aged 45-75 years treated between January 2022 and February 2023 were retrospectively analyzed. Eleven patients (Group A) received wound debridement, antibiotic-loaded bone cement (ALBC) at stage 1 treatment, percutaneous transluminal angioplasty (PTA), wound debr

SUBMITTER: Zhang F 

PROVIDER: S-EPMC12696158 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature