Omega-3 Polyunsaturated Fatty Acids and Adipose Tissue Inflammation in Humans: A Scoping Review.

ABSTRACT: Adipose tissue (AT) inflammation is a topic of increasing interest given its role in initiating systemic subclinical inflammation. Evidence from preclinical studies suggests that n-3 polyunsaturated fatty acids (PUFAs) may ameliorate AT inflammation through various pathways. However, fewer data are available from humans, and existing studies are heterogeneous in design and findings. The objective of this scoping review was to identify, review, and map the current literature on the relationship between n-3 PUFAs and AT inflammation in healthy humans. MEDLINE, EMBASE, and Cochrane databases were searched from inception to August 4, 2022. Eligible studies included experimental trials and observational studies, enrolling nonpregnant adult study populations free of diagnosed chronic/infectious

SUBMITTER: Chon JE 

PROVIDER: S-EPMC12696357 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature