Patterns and risk factors of intracranial recurrence after surgical resection of brain metastases from malignant tumors.

ABSTRACT:

Background

The incidence of brain metastases is increasing, and surgical resection remains a key treatment modality. However, postoperative intracranial recurrence - including local recurrence (LR), distant brain recurrence (DBR), and leptomeningeal disease (LMD) - significantly impacts patient prognosis. Previous studies have predominantly focused on single tumor types and lacked systematic analyses of recurrence patterns and risk factors.

Objectives

This study aimed to investigate the incidence, temporal distribution, and independent risk factors associated with distinct postoperative recurrence patterns.

Methods

Demographic, imaging, surgical, pathological, and post-treatment data from 198 patients who underwent resection of brain metastases were retrospectively an

SUBMITTER: Yin Q 

PROVIDER: S-EPMC12696531 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature