Awake Prone Positioning in Patients With COVID-19 Respiratory Failure: A Randomized Clinical Trial.

ABSTRACT:

Importance

Awake prone positioning (APP) has shown inconstant associations with improved clinical outcomes in nonintubated patients with COVID-19 developing severe pneumonia.

Objective

To evaluate the effects of APP on the need for intubation or incidence of death among patients with COVID-19-related hypoxemic respiratory failure.

Design, setting, and participants

This randomized clinical trial was conducted at 20 hospitals in France and 1 hospital in Mexico between July 2020 and August 2021. The study included patients from wards and intensive care units. Adult patients (18 years or older) who were not intubated and required at least 3 L/min of oxygen flow due to COVID-19 infection were included and randomly assigned in a 1:1 ratio to either APP or standard care. Int

SUBMITTER: Harrois A 

PROVIDER: S-EPMC12696593 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature