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Multiscale modes of functional brain connectivity.


ABSTRACT: Information processing in the brain spans from localised sensorimotor processes to higher-level cognition that integrates across multiple regions. Interactions between and within these subsystems enable multiscale information processing. Despite this multiscale characteristic, functional brain connectivity is often either estimated based on 10-30 distributed modes or parcellations with 100-1000 localised parcels, both missing across-scale functional interactions. We present Multiscale Probabilistic Functional Modes (mPFMs), a new mapping which comprises modes over various scales of granularity, thus enabling direct estimation of functional connectivity within- and across-scales. Crucially, mPFMs were not formulated, but emerged from data-driven multilevel Bayesian modelling of large

SUBMITTER: Farahibozorg SR 

PROVIDER: S-EPMC12696669 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature