Patient selection and outcome in low-grade glioma surgery.

ABSTRACT:

Background and objectives

Maximal safe resection is the cornerstone of diffuse low-grade glioma (dLGG) management, although epidemiological data are limited. We aim to explore surgical selection, techniques, and outcomes in a population-based cohort.

Materials and methods

This study utilized a multi-center case series (9 out of 10 neurosurgical departments in Norway and Sweden) of all adults (≥18 years) with histopathologically verified supratentorial dLGG, WHO grade 2, undergoing primary surgery from 2012-2017. Complications within 30 days and neurological outcomes at 3 months were assessed. Pre- and postoperative MRIs were reviewed centrally, blinded to patient outcome and center.

Results

Of 517 included patients, 217 (41.7%) were female, and the mean (SD) age was 4

SUBMITTER: Jensdottir M 

PROVIDER: S-EPMC12696705 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature