Strategies for community-sourced biocuration in bioinformatics: a case study on MIBiG 4.0.

ABSTRACT: Biocuration is essential to transform molecular sequence data into standardized, machine-readable resources. Such curated datasets enable comparative analysis, predictive modeling, and data integration across bioinformatics platforms. While professional biocuration is resource-intensive and usually limited to institutional settings, community-driven approaches can mobilize large-scale annotation of specialized datasets and are more resilient to disruptions in scientific funding. Here, we present a model for community-powered curation applied to the Minimum Information about a Biosynthetic Gene Cluster (MIBiG) repository. Through a framework of workflows for metadata capture, annotation validation, and contributor coordination, the MIBiG 4.0 initiative recruited 267 scientists across 178 in

SUBMITTER: Blin K 

PROVIDER: S-EPMC12696713 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature