Synthesis, Photophysical Properties, and Practical Hg(II)-Sensing Applications of a Rigidified Phenolo-Merocyanine Dye.

ABSTRACT: Among the strategies available to improve photophysical properties of organic fluorophores intended for imaging and sensing, structural modifications allowing for scaffold rigidification are particularly effective for enhancing yellow emission and photostability. In order to develop novel high-performance phenolic fluorophores, we have explored the synthesis of a conformationally restrained analog of flexible Brooker's merocyanine. We had the idea of applying a rigidification approach previously devised for cyanine dyes. Thus, the implementation of an acid-catalyzed domino double cyclization process allowed the synthesis of fluorescent phenol KR306. A comprehensive photophysical study has highlighted its outstanding optical properties in neutral aq. buffered conditions (a brightness of 71,

SUBMITTER: Renault K 

PROVIDER: S-EPMC12696781 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature