Early enteral nutrition combined with supplemental parenteral nutrition vs. total parenteral nutrition after pancreaticoduodenectomy: a retrospective and propensity score-matched analysis of postoperative complications.

ABSTRACT:

Background

Postoperative nutritional support strategy after pancreaticoduodenectomy (PD) remains controversial. This retrospective study aims to evaluate early enteral nutrition (EEN) combined with supplemental parenteral nutrition (SPN) vs. parenteral nutrition (PN) as postoperative nutritional support, focusing on early clinical outcomes and postoperative complications in patients who underwent PD.

Methods

Clinical data from consecutive patients who underwent PD between January 2022 and July 2024 were collected and analyzed in this retrospective study. The primary outcome was the incidence of postoperative complications. The secondary outcomes included specific postoperative complications, such as delayed gastric emptying (DGE), bile leak (BL), chyle leak (CL), acute pancr

SUBMITTER: Li J 

PROVIDER: S-EPMC12696965 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature