Lesion Depth Optimization in High-Power Radiofrequency Ablation: Evaluating Single High-Power and Combined Very High-Power Applications.

ABSTRACT:

Background

A very high-power short-duration (vHPSD) radiofrequency (RF) ablation creates shallower lesions, which may be insufficient in thick myocardial regions.

Aims

To clarify an effective ablation strategy following the initial vHPSD application and determine the best approach to create sufficient lesion depth in thick myocardial regions using ex vivo and in vivo models.

Methods

Lesion metrics were compared under various settings: 35 W versus 50 W with the same target ablation index (AI) (Step 1); double vHPSD ablations versus vHPSD followed by AI-guided ablation (Step 2); double applications (DA) with vHPSD followed by AI-guided ablation with a target AI of 450 versus single application (SA) with a target AI of 550 at 50 W (Step 3).

Results

Lesion depth wa

SUBMITTER: Iwakawa H 

PROVIDER: S-EPMC12697236 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature