Middle Meningeal Artery Embolization with n-Butyl Cyanoacrylate for the Treatment of Subdural Hematomas: The MEMBRANE Study Design.

ABSTRACT:

Background

Middle meningeal artery embolization with a liquid embolic is a minimally invasive adjunctive endovascular treatment for chronic subdural hematoma (cSDH). TRUFILL n-butyl cyanoacrylate Liquid Embolic System provides a possible option for middle meningeal artery embolization. The aim of this study is to evaluate safety/effectiveness of TRUFILL n-butyl cyanoacrylate versus standard-of-care alone for middle meningeal artery embolization in patients with cSDH.

Methods

MEMBRANE (Middle Meningeal Artery Embolization for the Treatment of Subdural Hematomas With TRUFILL n-BCA) is a prospective, multicenter, open-label, randomized-controlled trial enrolling ∼376 adults at ∼35 sites in the United States and China. Site physicians will determine whether participants will und

SUBMITTER: Kellner CP 

PROVIDER: S-EPMC12697590 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature