Significance of Subtle Diffusion Weighted Imaging Lesion Dynamics: A Comparative Analysis of Methods for Detecting Diffusion Weighted Imaging Lesion Reversal in Endovascular Stroke Treatment.

ABSTRACT:

Background

Restrictive diffusion on magnetic resonance imaging is recognized as an early marker of ischemic brain damage, even though diffusion-weighted imaging lesion reversal (DWI-R) is well known. This study aimed to compare methodologies for detecting DWI-R, including voxel-based analysis, which captures subtle lesion dynamics, and to test their correlation with clinical outcomes.

Methods

We retrospectively analyzed magnetic resonance imaging data from 216 consecutive patients with acute ischemic stroke obtained before and after endovascular therapy. DWI-R was defined either as an increase in DWI-Alberta Stroke Program Early Computed Tomography Score, a decrease of total DWI signal volume or as partial reversal of the initial DWI lesion, irrespective of the final DWI loa

SUBMITTER: Skattor TH 

PROVIDER: S-EPMC12697595 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature