Intraprocedural Technical Events During Flow Diverter Implantation Partially Mediate the Effect of Age on Aneurysm Occlusion.

ABSTRACT:

Background

Flow diverters (FDs) are the first line of treatment for specific intracranial aneurysms. However, aneurysm persistence at follow-up presents in up to 25%. Occlusion after flow diversion in older patients seems less effective due to clinical, anatomical, and physiological characteristics. We aimed to study the effect of age on aneurysm occlusion mediated by intraprocedural technical events.

Methods

We conducted a pooled analysis of 2 cohorts, including patients with unruptured saccular aneurysms in the internal carotid artery, treated with the Surpass Streamline FD. Multivariable logistic regression was used to identify predictors of complete occlusion at 12-month follow-up. A mediation analysis was performed to assess the role of intraprocedural technical events

SUBMITTER: Vivanco-Suarez J 

PROVIDER: S-EPMC12697608 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature