Association Between Estimated Pulse Wave Velocity and Endovascular Thrombectomy Outcome: A Secondary Analysis of the OPTIMAL-BP Trial.

ABSTRACT:

Background

The link between arterial stiffness, measured by estimated pulse wave velocity (ePWV), and outcomes following endovascular thrombectomy (EVT) has not been tested. This study aimed to determine whether ePWV predicts post-EVT outcome in patients with acute ischemic stroke.

Methods

This was a secondary analysis of the OPTIMAL-BP (Outcome in Patients Treated With Intraarterial Thrombectomy-Optimal Blood Pressure Control) trial, which enrolled 302 EVT patients from 19 stroke centers in South Korea between June 18, 2020 and November 28, 2022. The ePWV was calculated using a regression equation based on age and mean blood pressure (BP) at trial enrollment: ePWV = 9.587-0.402×age+4.560×10^-3×age²-2.621×10^-5×age²×mean BP+3.176×10<

SUBMITTER: Han M 

PROVIDER: S-EPMC12697619 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature