Perceptual Learning Based on Adaptive Contrast Detection Training for Intermittent Exotropia: A Pilot Double-Masked Randomized Controlled Study.

ABSTRACT:

Purpose

This pilot randomized clinical study investigated the effects of individualized adaptive perceptual learning on control scores, stereopsis, and ocular alignment in children with intermittent exotropia (IXT).

Methods

A total of 56 children with basic-type IXT (5-14 years old) were randomly assigned to either an experiment or placebo group, with 50 subjects included in the final analysis after excluding six participants due to poor adherence or incomplete follow-up. The experimental group underwent 30 days of individualized adaptive contrast detection training at their respective cutoff spatial frequencies, and the placebo group trained at a fixed low spatial frequency (3 cycles/degree). Primary outcome measures were control scores (near and distance). Secondary outcom

SUBMITTER: Han M 

PROVIDER: S-EPMC12697688 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature