Association Between Statin Use and Glaucoma Risk: A Population-Based Study.

ABSTRACT:

Purpose

To investigate the association between statin use and glaucoma risk.

Methods

This is a nationwide nested case-control study including adults with hyperlipidemia from the Taiwan National Health Insurance Research Database between 2009 and 2020. Cases were individuals newly diagnosed with ocular hypertension, primary open-angle glaucoma (POAG), or normal tension glaucoma (NTG). Controls were individuals without any subtypes of glaucoma. Prescription records for statins, fibrates, and other cholesterol-lowering medications were collected. Logistic regression models were applied to assess the association between medication exposure and the risk of glaucoma.

Results

The final analysis included 32,640 participants with ocular hypertension, 20,390 with POAG, 9945 wit

SUBMITTER: Pan SY 

PROVIDER: S-EPMC12697695 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature