The Relationship of Photopic and Mesopic Contrast Sensitivity to Retinal-Choroidal Structural Characteristics in Low-to-Moderate and High Myopia.

ABSTRACT:

Purpose

This study aimed to compare photopic and mesopic contrast sensitivity (CS) between low-to-moderate myopia (LMM) and high myopia (HM) groups, and to evaluate the associations between CS and chorioretinal structural and vascular parameters.

Methods

In this cross-sectional study, 108 participants were divided into an LMM group (n = 53, mean age = 21.0 years, mean SE = -4.25 diopters [D]) and an HM group (n = 55, mean age = 24.0 years, mean SE = -8.25 D). CS was tested under photopic (85 cd/m²) and mesopic (3 cd/m²) conditions. Chorioretinal parameters were measured using swept-source optical coherence tomography/optical coherence tomography angiography (SS-OCT/OCTA). Associations were assessed using univariate and stepwise multiple linear regression analyses.

Results

SUBMITTER: Lin M 

PROVIDER: S-EPMC12697708 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature