Trends and determinants of 23-valent pneumococcal polysaccharide vaccine revaccination among older adults in Shanghai, China, 2013-2023: A database-based study.

ABSTRACT: Pneumococcal disease remains a significant public health concern among older adults in China. The 23-valent pneumococcal polysaccharide vaccine (PPV23) has been shown to reduce the incidence of pneumococcal diseases, and timely revaccination helps maintain high levels of protective antibodies. However, data on PPV23 revaccination practices in this population remain limited. This study analyzed vaccination records from Shanghai's Immunization Program Information System (2013-2023) to evaluate PPV23 revaccination rates, temporal trends, and associated determinants (gender, household registration, residence, type of first dose, other vaccination history) among older adults. Joinpoint regression assessed temporal trends, while a 1:1 matched case-control analysis with conditional logistic regre

SUBMITTER: Wan K 

PROVIDER: S-EPMC12698045 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature