Near-infrared-II pulsed laser diode array for spectral photoacoustic imaging of deep tissue oxygenation.

ABSTRACT: Spectral photoacoustic imaging (sPAI) has the potential to detect clinically relevant measurements of blood oxygenation, non-invasively in real time. The unique advantage of sPAI is its ability to probe optical chromophores at extended imaging depths compared to purely optical modalities. PA imaging has previously been demonstrated using benchtop nanosecond pulsed solid-state lasers; however, their size and high cost limit the potential for clinical translation. Microfabricated pulsed laser diodes (PLDs) are miniaturized laser sources that can be fabricated and integrated at relatively low cost; however, microfabricated PLDs have been minimally investigated for the generation of photoacoustic signals due to the significantly lower energies they typically provide. In this work, we integrate

SUBMITTER: Vincely VD 

PROVIDER: S-EPMC12698089 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature