Prenatal exposure to adverse life events and autism and autistic-like traits in children in the Norwegian Mother, Father and Child Cohort Study (MoBa).

ABSTRACT:

Background

Mothers' experience of adverse life events (ALEs, e.g., divorce, bereavement, injury) during pregnancy has been linked with neurodevelopmental conditions like autism, and related traits like social communication difficulties and repetitive behavior in children. However, both the cumulative association and the underlying mechanism are unclear, and these associations might be confounded by unmeasured genetic or other early environmental factors shared within families.

Method

This longitudinal population-based cohort study included 114,247 children, born in Norway between 1999 and 2009, who participated in the Norwegian Mother, Father and Child Cohort Study. During week 30 of pregnancy, mothers of 51,940 children (of whom 12,597 were siblings) reported whether they h

SUBMITTER: Kanina A 

PROVIDER: S-EPMC12698280 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature