Evaluating the prognostic significance of the modified prognostic nutritional index-C-reactive protein-to-albumin-to-lymphocyte index in acute decompensated heart failure: special attention to the impact of diabetes.

ABSTRACT:

Objective

Malnutrition is one of the most common complications in acute decompensated heart failure (ADHF). This study investigated the predictive value of a modified prognostic nutritional index (PNI)-the C-reactive protein-to-albumin-to-lymphocyte (CALLY) index-for short-term mortality in ADHF patients, while accounting for the potential interactive effects of participants' glycemic status.

Method

The data were derived from the Jiangxi-ADHF II study cohort, which included 1,225 ADHF patients. The Boruta algorithm was employed to identify key prognostic features associated with mortality in ADHF and rank their predictive importance. Subsequently, multivariate Cox regression analysis and receiver operating characteristic curve analysis were conducted to evaluate and compare

SUBMITTER: Zhang N 

PROVIDER: S-EPMC12698377 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature