Comparison of apparent diffusion coefficient values in sentinel lymph nodes versus primary tumors for gastric cancer N staging.

ABSTRACT:

Purpose

To explore the differences in apparent diffusion coefficient (ADC) values based on the primary tumor and sentinel lymph node (SLN) for predicting N stages of gastric cancer (GC).

Methods

One hundred and sixty histopathologically confirmed GC patients between April 2021 and October 2024 were prospectively recruited. Preoperative DW-MRI was performed, and ADC values from primary tumors (ADC_T) and SLNs (ADC_LN), along with their relative ratios (rADC_T, rADC_LN), were measured. Differences in these parameters across N stages were analyzed using the Kruskal-Wallis test. Receiver operating characteristic analysis was used to evaluate their diagnostic performances for predicting N0 vs. N1-3 stages, N0 + 1 vs. N2 + 3 stages, and N0 +

SUBMITTER: Yan LL 

PROVIDER: S-EPMC12698429 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature