Pharmacological and toxicological insights into the ayurvedic formulation Rasasindura.

ABSTRACT: The current study explores the safety of Rasasindura (RS), an Ayurvedic herbo-metallic preparation containing mercury, and its therapeutic potential against oligospermia. Based on global concerns due to the toxicity of mercury, this study was designed to evaluate the toxicology and pharmacology of RS. Wistar rats were administered therapeutic and high doses of RS intragastrically for the in vivo toxicology study. The toxicity tests showed no significant changes in the major functions of organs, hematological and biochemical functions except mild hyperactivity in a few animals in the high dose group. The study's histopathological and biochemical analyses revealed no significant morphological or functional abnormalities in the brain, liver, kidneys, or testes of rats administered with high d

SUBMITTER: Kamath SU 

PROVIDER: S-EPMC12698811 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature