Evaluation of silver nitroprusside nanoparticles: selective toxicity against MCF-7 cells and in vivo antitumor activity.

ABSTRACT: A number of different metallic nanoparticles have been extensively investigated in recent years owing to their diverse potential biomedical and cancer applications, antibacterial activities, and chemical properties. Here, silver nitroprusside nanoparticles (AgNPs) were prepared from silver nitrate and sodium nitroprusside, and their anticancer activity was evaluated. AgNPs were prepared and characterized using Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), scanning electron microscopy (SEM), X-ray dispersive energy spectroscopy (EDX), and transmission electron microscopy (TEM). In vitro tests were performed using two breast cancer cell lines, a non-malignant breast epithelial cell line (MCF-10A), and a breast cancer cell line (MCF-7). The results obtained from cyt

SUBMITTER: Fernandes DS 

PROVIDER: S-EPMC12698880 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature