Risk factors analysis for pathological upgrade after endoscopic submucosal dissection in patients with gastric intraepithelial neoplasia: a single-center retrospective study.

ABSTRACT:

Background

Gastric intraepithelial neoplasia (GIN) is a key precancerous lesion of gastric cancer, and discrepancies between preoperative endoscopic forceps biopsy (EFB) pathology and postoperative pathology after endoscopic submucosal dissection (ESD) pose significant challenges for accurate diagnosis and treatment planning.

Objective

To analyze the risk factors for pathological upgrade in patients with GIN after an ESD procedure.

Design

Retrospective study.

Methods

A retrospective analysis was conducted on 682 patients diagnosed with GIN by gastric EFB pathology at the Digestive Endoscopy Center of Wuxi People's Hospital from January 2018 to December 2024 (490 with low-grade intraepithelial neoplasia (LGIN) and 192 with high-grade intraepithelial neoplasia (H

SUBMITTER: Ding L 

PROVIDER: S-EPMC12699007 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature