Effects of pasture consumption and obesity on insulin dysregulation and adiponectin concentrations in UK native-breed ponies.

ABSTRACT:

Background

Insulin dysregulation (ID) and hypoadiponectinaemia (total [adiponectin] <7.9 μg/mL) are risk factors for laminitis. They are sometimes, but not always, associated with obesity.

Objectives

To investigate the effects of pasture consumption and obesity on ID and circulating total [adiponectin] in ponies.

Study design

Longitudinal.

Methods

Seven native-breed ponies with normal basal and post-oral sugar test (OST) [insulin] and body condition score (BCS) 4.3-5.5/9 were allowed to graze until they reached BCS 7/9. Ponies were then maintained at BCS 7/9 until completion of the study (week 22). Morphometric measures, OST, insulin tolerance test (ITT), plasma [adiponectin], whole-blood expression of receptors for adiponectin, insulin, and insulin-like growth

SUBMITTER: Barnabe MA 

PROVIDER: S-EPMC12699113 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature