Reduced-Symmetry Homoleptic Pd₂L₄ Cages Stabilized by Noncovalent π-Interactions.

ABSTRACT: Low symmetry molecular cages are synthetically challenging yet may have important applications. Symmetry in coordination cages is typically broken by repulsive design leveraging steric clashes, geometric mismatches, or orthogonal ligands. Here, we demonstrate a contrasting strategy exploiting attractive π-interactions from a sole symmetric bipyridyl ligand L^F bearing an endohedrally-pendant pentafluorobenzyl ether to guide the self-assembly of low-symmetry, homoleptic cages. Ligand L^F formed lantern-type Pd₂L₄ cages that adopt a single, low-symmetry conformer-stabilized by both π-stacking and tetrafluoroborate encapsulation-demonstrated by crystallographic and spectroscopic characterization. Cage assembly with L^F contrasted the control

SUBMITTER: Poole DA 

PROVIDER: S-EPMC12699168 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature