Cue-Elicited Brain Activity and Treatment Outcomes in Substance Use Disorders: A Meta-Analysis.

ABSTRACT:

Importance

Substance use disorders (SUDs) affect millions of of people worldwide and are marked by high relapse rates. Cue-elicited brain activity may correlate with treatment success, but no meta-analysis has identified which brain regions are consistently associated with outcomes.

Objective

To evaluate, across the existing literature, whether functional magnetic resonance imaging (fMRI)-based cue reactivity is associated with SUD treatment response (eg, predictive biomarker) or posttreatment neural changes (eg, response biomarker).

Data sources

A systematic search of PubMed, PsycINFO, Embase, and Cochrane databases covered studies published from database inception through May 2023.

Study selection

Studies were included if they reported fMRI-based cue reactivi

SUBMITTER: Evohr B 

PROVIDER: S-EPMC12699361 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature