Neural correlates of increased alcohol demand following alcohol cue exposure in adult heavy drinkers.

ABSTRACT: Alcohol use disorder is associated with overvaluation of alcohol relative to other rewards, in part due to dynamic increases in value in response to alcohol-related cues. In a neuroeconomic framework, alcohol cues increase behavioral economic demand for alcohol, but the neural correlates these cue effects are unknown. This functional magnetic resonance imaging study combined a neuroeconomic alcohol purchase task with an alcohol cue exposure in 72 heavy drinkers with established sensitivity to alcohol cues (51 % female; mean age=33.74). Participants reported how many drinks they would consume from $0-$80/drink following exposure to neutral and alcohol images in a fixed order. Participants purchased significantly more drinks in the alcohol compared to the neutral condition, which was also ev

SUBMITTER: Amlung M 

PROVIDER: S-EPMC12699869 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature