Culturally relevant settings for TB transmission in an African city with endemic TB.

ABSTRACT:

Background

TB persists because Mycobacterium tuberculosis (M. tb) is transmitted through unknown community contact networks. This transmission occurs in culturally relevant settings as infectious cases go about their daily lives. We performed a prospective cohort study in Kampala, Uganda, to estimate incident TB infection (TBI) and relate it to time spent in a broad array of settings.

Methods

In a prospective cohort study of 1,275 adult residents without TBI, we measured cumulative incidence of infection at 1 year using the tuberculin skin test. We measured time spent in community settings using a validated questionnaire and related settings to incident infection using Poisson regression analysis.

Results

The settings visited by participants varied by we

SUBMITTER: Quach THT 

PROVIDER: S-EPMC12699961 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature