Photographic evaluation of clinical activity score in thyroid eye disease.

ABSTRACT:

Purpose

Given the subjective nature of clinical activity score (CAS) and variability between observers, this study evaluated the inter-observer variability of soft tissue signs (STS) in the CAS using periocular photographs and compared the diagnostic performance of photographic CAS (P-CAS) with clinical assessment for detecting active thyroid eye disease (TED).

Methods

This retrospective cohort study included 754 TED patients who underwent periocular photography at Seoul National University Bundang Hospital between 2006 and 2021. Five oculoplastic specialists independently evaluated five STS of CAS using periocular photographs. Inter-observer agreement and concordance between photographically (P-STS) and clinically (C-STS) assessed STS, assessment consistency, were analyzed

SUBMITTER: Lee GM 

PROVIDER: S-EPMC12700362 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature