Efficacy and safety of PM-AR-T versus edwards MC3 rings in tricuspid regurgitation: A non-inferiority, randomized controlled trial.

ABSTRACT:

Objectives

Tricuspid valve repair, particularly with annuloplasty rings, is increasingly recognized as an effective treatment. PM-AR-T is a semi-rigid annuloplasty ring based on a nickel-titanium alloy which has made progress in animal models, however, studies on PM-AR-T's performance in patients with tricuspid regurgitation (TR) are lacking. This study aimed to compare the efficacy and safety of the PM-AR-T with the Edwards MC3 ring for the TR treatment.

Methods

A non-inferiority, randomized controlled trial was conducted in 20 centers across China, enrolling patients with tricuspid valve disease requiring surgical repair. Patients were randomized to receive either PM-AR-T or Edwards MC3 ring. The primary endpoint was the success rate of valve repair at 6 months.

Results

SUBMITTER: Xu Z 

PROVIDER: S-EPMC12700415 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature